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As ostarine is generally run for eight weeks without any trouble, it is generally chosen as an alternative to anabolic steroids to a general re-comping effectof a normal diet or other supplement, with ostarine having a much higher bioavailability than steroids. The human body can store over 1% ostarine, in comparison to only 1% in the body after ingestion of a high fat diet, in a healthy diet for six months.[4] Mechanisms Ostarine is a naturally occurring neurotransmitter in the brain, which acts at multiple different mechanisms to regulate mood and emotion. At the cellular level, ostarine regulates brain activity by increasing blood flow by acting as an anabolic steroid. Ostarine also plays a role as a neuromodulator by increasing the activity of various neurotransmitters like norepinephrine, serotonin, dopamine, GABA, histamine and melatonin, among others.[5] Ostarine is an anti-stress chemical known to play a role in cognition.[6] In the short term, an increase in serotonin synthesis appears to help reduce anxiety and depression, while in the long-term such an increase in serotonin may contribute to a decrease in depression and anxiety through reducing their impact on cognitive function. [6] Ostarine is also known to decrease cortisol levels and increase the levels of androgen receptors in various body systems. [6] Ostarine was also shown in vitro to reduce the effects of oxidative stress in mitochondria.[7] Ostarine is known to increase muscle activity and strength, and as such the osterine concentration in the urine may be beneficial in recovery from muscular fatigue.[8][9] Studies assessing the efficacy of different dosages of ostarine for bodybuilders has found a significantly greater efficacy of ostarine when compared to a placebo or an androgen receptor antagonist.[10][11][12] In rodents, ostarine appears to increase fat mass in male Sprague Dawley rats.[13] Toxicity Ostarine can be highly toxic due to the ability to stimulate the synthesis of androgens, which can induce side effects such as prostate cancer in rats[14] and in humans.[15][16] It is known that excessive supplementation of ostarine can have high toxicity to kidneys and liver, and also can cause an imbalance in the blood sugar levels, which can lead to a dangerous overdose on blood glucose.[17] It is also known that prolonged ostarine ingestion may be toxic, with overfeeding and excessive ostarine ingestion, similar to the "sugar Similar articles:
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